Clinical and Toxico-pathological Parameters for Deoxynivalenol Intoxication in B6C3F1 Mice

Clinical, laboratory and pathological findings in sub-acute monensin intoxication in goats

Toxic effects of monensin, a polyether antibiotic mainly used as a coccidiostat, have been described in a wide range of animals. The present study was performed to investigate the toxic effects of monensin in goats. Seven adult goats were administered sodium monensin, 13.5 mg kg-1, daily for five consecutive days via gastric gavage. Monensin toxicity was evaluated by clinical signs, serum bioch...

Clinical and laboratory parameters in dapsone acute intoxication.

OBJECTIVE To determine the severity of dapsone (DDS) acute intoxication - an uncommon medical event - using clinical and laboratory parameters. METHODS Two hundred and seventy four patients with acute DDS intoxication, aged 1 month to 50 years old, were studied and classified into four age groups. Clinical evaluation was assessed through a protocol and correlated with laboratory parameters. S...

clinical, laboratory and pathological findings in sub-acute monensin intoxication in goats

toxic effects of monensin, a polyether antibiotic mainly used as a coccidiostat, have been described in a wide range of animals. the present study was performed to investigate the toxic effects of monensin in goats. seven adult goats were administered sodium monensin, 13.5 mg kg-1, daily for five consecutive days via gastric gavage. monensin toxicity was evaluated by clinical signs, serum bioch...

RDX and miRNA Expression in B6C3F1 Mice

Plasma haptoglobin and immunoglobulins as diagnostic indicators of deoxynivalenol intoxication

This study aimed to discover potential biomarkers for dioxynivalenol (DON) intoxication. B6C3F1 male mice were orally exposed to 0.83, 2.5 and 7.5 mg/kg body weight (bw) DON for 8 days and the differential protein expressions in their blood plasma were determined by SELDI - Time-of-Flight/Mass Spectrometry (TOF/MS) and the immunoglobulins (Igs) G, A, M and E in the serum were investigated. 11.7...